Assessment of readiness to wean an elderly patient from mechanical ventilation using clinical and diaphragmatic ultrasound predictors: a case report

Main Article Content

Sylvanus Ojum
Joy Omiepirisa Dayi

Abstract










Background: Weaning from mechanical ventilation is a critical and high-risk phase of intensive care management, particularly in elderly patients. One-fifth of mechanically ventilated patients experience difficulty during weaning and conventional clinical assessment may be unreliable, necessitating the use of objective physiological indices. Weaning predictors such as the rapid shallow breathing index and diaphragmatic ultrasonography have been shown to support decision-making when clinical evaluation is limited.


Aim: Report the use of combined clinical criteria and diaphragmatic ultrasound parameters in assessing readiness for weaning from mechanical ventilation in an elderly patient with cognitive impairment.


Case Report: A 70-year-old female with multiple ischaemic cerebrovascular accidents and vascular dementia was admitted following head trauma complicated by bilateral subdural haematomas. She underwent burr-hole evacuation and required postoperative mechanical ventilation with sedation. After 26 hours of ventilatory support, standard clinical criteria for weaning were fulfilled. Spontaneous breathing test was performed using low-level pressure support ventilation. Objective weaning predictors were assessed, including the rapid shallow breathing index and diaphragmatic ultrasound parameters. Rapid shallow breathing index was 38 breaths/min/L. Diaphragmatic ultrasonography demonstrated a diaphragm thickening fraction of 41.25% and a diaphragm excursion of 162 mm. Spontaneous breathing test was completed successfully without respiratory distress or haemodynamic instability.


Conclusion: This case highlights the clinical value of integrating conventional weaning criteria with diaphragmatic ultrasound assessment in elderly patients with neurological and cognitive impairment. Objective evaluation of diaphragmatic function enhances confidence in extubation decisions and may reduce the risk of weaning failure in complex clinical settings.









Downloads

Download data is not yet available.

Article Details

How to Cite
Assessment of readiness to wean an elderly patient from mechanical ventilation using clinical and diaphragmatic ultrasound predictors: a case report. (2026). Port Harcourt Medical Journal, 20(1), 63-67. https://doi.org/10.60787/phmj.v20i1.253
Section
Case Report

References

1.Esteban A, Frutos F, Tobin MJ, Alía I, Solsona JF, Valverdú I, et al. A comparison of four methods of weaning patients from mechanical ventilation. Spanish Lung Failure Collaborative Group. N England J Med 1995;332(6):345–350.

2.Schmidt GA, Girard TD, Kress JP, Morris PE, Ouellette DR, Alhazzani W, et al.; ATS/CHEST Ad Hoc Committee on Liberation from Mechanical Ventilation in Adults. Official executive summary of an American Thoracic Society/American College of Chest Physicians clinical practice guideline: liberation from mechanical ventilation in critically ill adults. Am J Respiratory Critical Care Med 2017;195(1):115–119.

3.MacIntyre NR, Cook DJ, Ely EW Jr, Epstein SK, Fink JB, Heffner JE, et al. Evidence-based guidelines for weaning and discontinuing ventilatory support. Chest 2001;120(6 Suppl):375S–395S.

4.Yang KL, Tobin MJ. A prospective study of indices predicting the outcome of trials of weaning from mechanical ventilation. N England J Med 1991;324(21):1445–1450.

5.Meade M, Guyatt G, Cook D, Griffith L, Sinuff T, Kergl C, et al. Predicting success in weaning from mechanical ventilation. Chest 2001;120(6 Suppl):400S–424S.

6.Sassoon CS, Mahutte CK. Airway occlusion pressure and breathing pattern as predictors of weaning outcome. Am Rev Respir Dis 1993;148(4 Pt 1):860–866.

7.Shi ZH, de Vries H, de Grooth HJ, Jonkman AH, Zhang Y, Haaksma M, et al. Changes in respiratory muscle thickness during mechanical ventilation: focus on expiratory muscles. Anesthesiology 2021;134(5):748–759.

8.Jaber S, Petrof BJ, Jung B, Chanques G, Berthet JP, Rabuel C, et al. Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans. Am J Respiratory Critical Care Med 2011;183(3):364–371.

9.DiNino E, Gartman EJ, Sethi JM, McCool FD. Diaphragm ultrasound as a predictor of successful extubation from mechanical ventilation. Thorax 2014;69(5):423–427.

10.Emre G, Acosta D, Baston C. Diaphragm ultrasound for assessing diaphragmatic function and predicting ventilator weaning success: a review of the literature. Curr Pulmonol Rep 2025;14:33.

11.Ueki J, de Bruin PF, Pride NB. In vivo assessment of diaphragm contraction by ultrasound in normal subjects. Thorax 1995;50(11):1157–1161.

12.Kim WY, Suh HJ, Hong SB, Koh Y, Lim CM. Diaphragm dysfunction assessed by ultrasonography: influence on weaning from mechanical ventilation. Critical Care Med 2011;39(12):2627–2630.

13.Pirompanich P, Romsaiyut S. Use of diaphragm thickening fraction combined with rapid shallow breathing index for predicting success of weaning from mechanical ventilator in medical patients. J Intensive Care 2018;6(1):6. Erratum in: J Intensive Care 2018;6:25.

14.Li S, Chen Z, Yan W. Application of bedside ultrasound in predicting the outcome of weaning from mechanical ventilation in elderly patients. BMC Pulm Med 2021;21(1):217.

15.Lin H, Yao M, Qin Z, Fu S, Wang H. Predictive values of ultrasonic diaphragm thickening fraction combined with integrative weaning index in weaning patients with mechanical ventilation: a retrospective study. J Cardiothorac Surg 2024;19(1):66.

16.Mahmoodpoor A, Fouladi S, Ramouz A, Shadvar K, Ostadi Z, Soleimanpour H. Diaphragm ultrasound to predict weaning outcome: systematic review and meta-analysis. Anaesthesiol Intensive Ther 2022;54(2):164–174.

17.Dubé BP, Dres M, Mayaux J, Demiri S, Similowski T, Demoule A. Ultrasound evaluation of diaphragm function in mechanically ventilated patients: comparison to phrenic stimulation and prognostic implications. Thorax 2017;72(9):811–818.

18.Huang HY, Huang CY, Li LF. Prolonged mechanical ventilation: outcomes and management. J Clinical Med 2022;11(9):2451.

19.Epstein SK. Weaning from mechanical ventilation. Respir Care 2002;47(4):454–468.

Similar Articles

You may also start an advanced similarity search for this article.